منابع مشابه
Principles and Mechanisms of Patterning
If development is the process of reproducibly taking undifferentiated tissue and making it more complex in an organized way, then pattern formation is the mechanism for producing the organization in that complexity. This requires initiating differential gene expression within two or more apparently homogeneous cells. In some organisms this is initially done by segregating cytoplasmic determinan...
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The dorsoventral (DV) patterning of the early Drosophila embryo depends on Dorsal, a maternal sequence-specific transcription factor related to mammalian NF-kappaB. Dorsal controls DV patterning through the differential regulation of approximately 50 target genes in a concentration-dependent manner. Whole-genome methods, including ChIP-chip and ChIP-seq assays, have identified approximately 100...
متن کاملPatterning mechanisms controlling vertebrate limb development.
Vertebrate limb buds are embryonic structures for which much molecular and cellular data are known regarding the mechanisms that control pattern formation during development. Specialized regions of the developing limb bud, such as the zone of polarizing activity (ZPA), the apical ectodermal ridge (AER), and the non-ridge ectoderm, direct and coordinate the development of the limb bud along the ...
متن کاملMechanisms of non-enzymatic antioxidant defense system of different organs of Catharanthus roseus for protective of cell membrane
Background & Aim: When the level of free radicals is increased and also when both the enzymatic systems and low molecular antioxidants are not sufficient to protect the organism, it seems necessary to get antioxidants from external sources. This study aimed to evaluate the antioxidant potential of different parts of Catharantus roseus Experimental: The antioxidant potential of ethanol...
متن کاملLeft-right patterning: conserved and divergent mechanisms.
The left-right (LR) asymmetry of visceral organs is fundamental to their function and position within the body. Over the past decade or so, the molecular mechanisms underlying the establishment of such LR asymmetry have been revealed in many vertebrate and invertebrate model organisms. These studies have identified a gene network that contributes to this process and is highly conserved from sea...
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ژورنال
عنوان ژورنال: Science
سال: 2008
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1162783